At the same time the surgeons connect a heart-ung machine to the two suppying and draining bood vesses of the iver creating a cosed circuit. “Before we get started with the toxic fush it must first be estabished that there is no eak into the boodstream says Vahrmeijer. “This is aso monitored during the actua perfusion with chemotherapy. We do this with radioactive red bood ces. Too much eakage is not aowed because that woud mean that the poison spreads throughout the body.
With fata consequences for the bone marrow. If it is determined that there is no eakage perfusion wi begin. “We use the drug Mephaan for this. It is a substance that not ony attacks ces that are B2C Email List dividing but aso ces that are not dividing. Tumor ces are more affected than iver ces.
How it works? A factor that may pay a roe is that heathy ces recover better from a confrontation with Mephaan than cancer ces and therefore survive at a high concentration. After fushing with a high concentration of Mephaan for an hour the iver must be rinsed thoroughy before reconnecting it to the boodstream. When that has happened the surgeons aso remove the gabadder because part of the poison coud be stored there.